Symptom Management in Hepatocellular Carcinoma

Symptom management in hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) annually causes about one million deaths. Because of advanced stage at diagnosis, HCC carries a five-year survival rate of less than 5% in patients diagnosed with unresectable disease. Incidence for HCC is higher in men and individuals of Asian descent, where viral hepatitis, a leading cause of HCC, is endemic. This article will provide an overview of the complex ...

Hepatocellular Carcinoma in Sheep

Hepatocellular carcinoma in a sheep

At necropsy of a five-year-old sheep, a pear shaped, lobular yellow-brownish mass measuring about 12 ×15 × 20 cm was found to involve the right hepatic lobe. Microscopic examination revealed two trabecularand solid patterns of neoplastic hepatocytes. In solid pattern, there were numerous tumoral giant cells thatcontain one or more large hyperchromatic bizarre-shaped nuclei scattered among clust...

Management of Hepatocellular Carcinoma

The rising incidence in the United States, as well as other parts of the world, is attributed largely to the increase in hepatitis C–related liver disease, a known risk factor for the disease.[2] In the United States alone, the seroprevalence of hepatitis C virus is estimated to be 3.9 million cases.[3] Other risk factors for HCC include hepatitis B viral infection, alcoholic cirrhosis, aflatox...

Medical management of hepatocellular carcinoma.

The possibility of effective treatment of hepatocellular carcinoma (HCC), one of the most common cancers worldwide, largely depends on its detection at an early stage before symptoms develop. Screening patients with known cirrhosis, in whom the overall annual incidence of HCC development is of the order of 1-6% (1,2), has the potential to improve the detection rate of such asymptomatic tumors. ...